Who can take part?
You may participate in the study if you:
- Are between 18 and 80 years of age
- Have been diagnosed with chronic cough associated with asthma or COPD, or chronic cough with unknown cause
You may not participate in the study if you:
- Are pregnant or breastfeeding
- Have had COVID-19 in the past 8 weeks
Certain pre-existing conditions and medications may make you unable to participate. The study doctor will discuss these with you if you are interested in participating.
People who are able to have children must agree to avoid becoming pregnant or fathering a child while participating in the study.
What is involved for you?
Participants in the study will undertake the following assessments, tests and procedures:
- Medical history
- Physical exam
- Electrocardiogram
- Neurological exam
- Blood tests
- Pregnancy tests (women who can have children only)
- Urine tests
- COVID-19 nasal swab
- Chest X-ray
- Health questionnaires
- Lung function tests
- Sputum sampling
- Test for reduction of coughing induced by Mannitol
- Take oral tablets twice a day containing study drug or placebo for 8 weeks
Trial dates
June 2023 to April 2024