Heated versus room temperature intra-peritoneal chemotherapy at the time of for stage III ovarian cancer surgical cytoreduction
Ovarian, Fallopian tube and Primary peritoneal Cancers
Recent research suggests that treatment with heated intra-peritoneal chemotherapy at the time of surgery cytoreduction may improve survival in women with ovarian cancer compared to standard intravenous chemotherapy. This clinical trial evaluates the safety and preliminary efficacy of intra-abdominal treatment with heated chemotherapy, at the time of surgery for ovarian cancer and cancers of the fallopian tubes and peritoneum (the lining of the abdomen).
The primary aim is to evaluate outcomes of using heated intra-peritoneal chemotherapy compared to chemotherapy at room temperature. The study also evaluates effects of treatment on participants’ quality of life and survival rates. A third aim of the study is to explore biological markers in the blood which have potential to improve diagnosis and treatment planning for women with ovarian cancer.