Yellowstone - A new treatment for Crohn’s Disease

Crohn’s Disease

Crohn’s disease is a chronic disease  that causes inflammation (swelling) in the bowel. People with Crohn’s disease often suffer from diarrhoea, abdominal pain, rectal bleeding, weight loss, and fever. There is no cure for Crohn’s disease. Available treatments only to help control the disease.

Ozanimod  is a chemical compound that is thought to act on the immune system by making certain types of white blood cells stay in the lymph nodes and other places in the body, keeping them away from sites of inflammation.

The purpose of this study is to see whether ozanimod is safe and effective for treatment of Crohn’s disease.

Trial Status
Active, not recruiting
Trial Phase
Phase 3 Drug Trial
Trial contact details
Contact Person
IBD Clinical Trials Unit
What you need to know

Who can take part?


  • Participants aged 12 to 75 years with a body weight ≥ 45 kg
  • Diagnosis of Crohn’s Disease for at least 3 months


  • Certain underlying health conditions may make you ineligible to participate
  • Previous surgical intervention for Crohn’s Disease
  • Current or recent infection
  • Pregnant or breastfeeding women may not participate
  • Previous cancer diagnosis
  • Some medications may make you ineligible to participate

What is involved for you?

  • Medical history and collection of demographic information
  • Vital signs
  • Electrocardiogram
  • Physical exam
  • Blood and urine tests
  • Pregnancy tests in women of childbearing potential
  • Stool tests
  • Colonoscopy with colon tissue biopsy
  • Eye exam
  • Lung function test
  • Daily diary completion
  • Questionnaires
  • Daily oral treatment

Trial dates

Sep 2019 – Dec 2023

All research clinical trials news

Mater researchers in Brisbane are leading a trial of a game-changing flu vaccine that has the potential to provide greater and more durable protection against the virus.



Mater launches trial of Australian-first flu vaccine

Stephanie Guilas has worked in many departments throughout Mater Hospital Brisbane, however, after 28 years of service, she found her true passion working within Mater Research’s Mothers and Babies...



Stephanie Guilas is improving outcomes for mums and bubs through research

Working as a research assistant in an immunology research lab, Yvonne Gautam learnt what a clinical trial was after being asked to set up a lab for a Phase Two clinical trial.



Clinical Trials Coordinator Yvonne Gautam is working towards creating better treatments for patients with diabetes

Displaying results 1-3 (of 16)
 |<  < 1 - 2 - 3 - 4 - 5 - 6  >  >|