Who can take part?
- People who have been recently diagnosed and not begun treatment for DLBCL, grade 3b Follicular Lymphoma and certain rare forms of B-cell lymphoma
- People with no prior history of blood cancers or other cancers, aside from some skin cancers
- People of reproductive potential must avoid pregnancy during the study
What is involved for you?
Participants will be randomly assigned to receive investigational drug plus standard chemotherapy, by intravenous infusion, or standard chemotherapy alone. They also undergo the following tests:
- Physical exams
- Heart rate & blood pressure
- Electrocardiogram
- Blood tests
- Urine tests
- Imaging scans: PET/CT
- CT or MRI scan
- Echocardiogram
- Bone marrow biopsy
- A tumour biopsy may be required, if samples from a diagnostic biopsy are not available
- Questionnaires