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We are investigating a nerve block treatment to help with pelvic pain in endometriosis

This study is testing whether a nerve block, called a superior hypogastric plexus (SHP) block, can help reduce pain in people with endometriosis. The SHP block is given during laparoscopic surgery and targets nerves that transmit pelvic pain. Participants in this study will receive either the nerve block or standard care during surgery. Researchers will then compare pain levels, medication use, and recovery between the two groups. The goal is to find out if this nerve block can improve pain control and quality of life after surgery for endometriosis.

What you need to know

Who can take part?

Adults diagnosed with endometriosis
Scheduled to have laparoscopic surgery for endometriosis
Experiencing ongoing pelvic pain
Able to give informed consent.

Who is ineligible to take part?

Pregnant or breastfeeding
Known allergy to local anaesthetics
Previous nerve block in the pelvis
Significant medical conditions that could affect participation
Unable to understand or complete study requirements.

What is involved for me?

Complete two short questionnaires (on pain and quality of life) before surgery
Undergo standard laparoscopic surgery for endometriosis
While under general anaesthesia, receive either:
a nerve block (SHP block) with local anaesthetic, or
a placebo injection (saline), chosen at random
After surgery, have your pain levels recorded at 2, 6, 12 and 24 hours
Your use of pain medications will be monitored while in hospital
Complete follow-up questionnaires at 3 and 6 months after surgery (in person or online)
All data will be collected confidentially, and participation is completely voluntary.

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